Healthy ageing · November 5, 2026
Older adults with the least inflammatory diet scores had 81% greater odds of favourable fitness. The study estimated VO2max — and cannot show diet caused it
A Guangzhou study paired a 79-item food questionnaire with a submaximal cycling test in 906 adults. The association was clearest among active participants, but diet, exercise and fitness can all travel together.

Can a diet score tell us anything about how well an older adult's heart and lungs support exercise? Researchers used data from 906 community-dwelling adults in the Guangzhou Nutrition and Health Study, with an average age of 65.9 years. A validated 79-item food-frequency questionnaire supplied the ingredients for a Dietary Inflammatory Index, while a submaximal cycling test supplied an estimate of aerobic fitness.
Lower index scores represent a diet calculated to be less inflammatory. Adults in the lowest third of the score had 81% greater odds of meeting one definition of favourable cardiorespiratory fitness than those in the highest third. The odds ratio was 1.81, with a 95% confidence interval from 1.22 to 2.70. Their estimated VO2max also followed a favourable trend across the diet groups, although the statistical evidence was only just below the usual threshold at p = 0.048.
The result depended on how fitness was defined. One definition placed people in the sex-specific top quarter of estimated VO2max. The other asked whether the cycling workload kept them below 85% of their predicted maximum heart rate. The diet score was associated with the VO2max-based result, but not clearly with the heart-rate result: the odds ratio was 1.31, with a confidence interval from 0.94 to 1.84.
Physical activity complicated the picture in a useful way. The association between a lower inflammatory score and higher estimated VO2max was stronger among active participants. Compared with people whose diet score stayed high, those who moved to a low score had three times the odds of favourable fitness, while those whose score stayed low had about two and a half times the odds. Both estimates were imprecise: their confidence intervals were 1.20 to 7.51 and 1.28 to 4.87.
Those numbers do not prove that an anti-inflammatory diet builds fitness. The paper describes the analysis as cross-sectional, diet was self-reported, and VO2max was estimated with a submaximal protocol rather than measured during an all-out laboratory test. People who are fitter or more active may shop, eat, sleep and manage health conditions differently. Statistical adjustment cannot remove every such difference, and a dietary index does not identify one food responsible for the association.
The practical reading is therefore modest: a varied diet rich in minimally processed plant foods and regular physical activity often fit into the same healthy-ageing pattern, and this study found that its diet score tracked with one fitness estimate. A trial that changes diet while holding exercise support constant would be needed to learn whether the diet itself improves aerobic capacity. Anyone with heart, lung or mobility limitations should choose activity with their clinician rather than treating a food score as an exercise prescription.
Diet score and two definitions of fitness
906
Community-dwelling older adults; 615 women and 291 men
65.9 years
Average age, with a standard deviation of 5.4 years
79 foods
Items in the validated food-frequency questionnaire used to calculate the diet score
OR 1.81
Lowest versus highest diet-inflammatory-score third for favourable VO2max; 95% CI 1.22–2.70
OR 1.31
Same comparison using the heart-rate definition; 95% CI 0.94–1.84, not statistically clear
OR 3.01
Moved from a high to low score versus stayed high; 95% CI 1.20–7.51
OR 2.49
Stayed at a low score versus stayed high; 95% CI 1.28–4.87
Cross-sectional analysis using food-frequency questionnaires and a submaximal cycle-ergometer protocol. VO2max was estimated with the age-corrected Åstrand–Ryhming nomogram. Favourable fitness meant either the sex-specific top quarter of estimated VO2max or completing the workload below 85% of predicted maximum heart rate. Odds ratios describe associations and do not establish that diet improved fitness.
- VO2max is the maximum rate at which the body can use oxygen during exercise. It can be measured directly from breathed gases or estimated from heart rate and workload, as in this study.
- The Dietary Inflammatory Index combines reported intakes of multiple foods and nutrients into one score based on their expected relationship with inflammatory markers. It is a research tool, not a diagnosis.
- An odds ratio of 1.81 means the odds were 81% higher; it does not mean 81% more participants were fit, and the abstract does not provide the absolute group percentages.
- The confidence interval around the diet-change estimate was wide: 1.20 to 7.51. That means the data support anything from a modest association to a very large one.
- The association differed by the fitness definition. That is one reason not to reduce the paper to a single headline number.
- The study was registered as NCT03179657 and used follow-up data collected between 2017 and 2021. The paper itself was published on 27 October 2026.
- Dietary Inflammatory Index and cardiorespiratory fitness among older adults living in the community: a cross-sectional analysisBritish Journal of Nutrition, 27 October 2026 · Primary study record; sample, questionnaire, cycling protocol, fitness definitions, odds ratios, confidence intervals and limitations checked against the indexed abstract.
- PubMed record 42934988US National Library of Medicine · Publication date, methods, results and trial-registration identifier.
- Walking, Skating, Cycling (8185331671).jpgWikimedia Commons · Photograph by Garry Knight, licensed CC BY 2.0; reused as a general activity illustration.
General information, not medical advice. This observational analysis cannot show that a particular diet improves cardiorespiratory fitness. If you have heart, lung, metabolic or mobility concerns, ask a qualified clinician or physiotherapist about safe activity and a dietitian about an appropriate eating pattern.
Analysis by NutroPractic from the sources listed. Written for general readers; it does not replace advice from your own doctor.
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