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Nutrition and mental health · November 7, 2026

Higher fibre intake first tracked with 35% lower suicide risk — then the association weakened after related nutrients entered the model

The 18.7-year Japanese cohort recorded 459 suicide deaths among 88,808 adults. The shift from hazard ratio 0.65 to 0.85 argues for a whole-diet signal, not a fibre cure.

A small heap of fine white table salt
Photo by Conall, CC BY 2.0, via Wikimedia Commons. Reused as a general nutrient-measurement illustration; not connected with the cohort.

The Japan Public Health Center cohort followed 40,630 men and 48,178 women, aged 44–76 at dietary assessment, for an average of 18.7 years. A validated food-frequency questionnaire estimated fibre intake, and 459 deaths from suicide were identified through December 2018.

After adjustment for several lifestyle and dietary factors, people in the highest quarter of total fibre intake had a hazard ratio of 0.65 compared with the lowest quarter, with a 95% confidence interval from 0.46 to 0.93. Vegetable and fruit fibre showed similar inverse associations, while cereal and bean fibre did not.

The interpretation changed when the model added folate, vitamin B6, magnesium and iron — nutrients strongly correlated with fibre-rich foods. The total-fibre hazard ratio moved to 0.85, with an interval from 0.55 to 1.31, no longer a clear association. Diet was measured rather than assigned, and depression at baseline was not fully captured. The findings point toward a broader food pattern or correlated circumstances; they do not show that fibre prevents suicide or treats mental illness.

Analysis by NutroPractic from the sources listed. Written for general readers; it does not replace advice from your own doctor.

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Higher fibre intake first tracked with 35% lower suicide risk — then the association weakened after related nutrients entered the model | NutroPractic